TB-500 is a synthetic peptide derived from the active region of thymosin beta-4, a naturally occurring protein involved in cell migration, angiogenesis, and tissue regeneration. Using only the bioactive fragment improves stability and shelf life compared with full-length TB-4.
Its primary characterized mechanism is regulation of actin polymerization within the cytoskeleton, with downstream effects on stem-cell recruitment, vascular formation, and inflammatory cytokine modulation.
- Cellular repair and stem-cell migration research
- Cardiovascular and dermal regeneration studies
- Tendon and ligament healing investigation
- Inflammatory cytokine and nerve-regeneration models
- MW
- ~4963.5
- Purity
- ≥99% (HPLC)
Lyophilized vial at -20 °C. Reconstituted solution stable at 2–8 °C for up to 20 days. Avoid repeated freeze-thaw cycles.
For research and laboratory use only. Not for human or veterinary consumption.
How to run this compound.
Add bacteriostatic water to the sealed vial. Swirl — do not shake. Refrigerate after reconstitution.
Reconstitute with bacteriostatic water. Subcutaneous administration on protocol cadence.
Run on the protocol schedule. The system rewards consistency over intensity.
Pair with complementary REFRAME lines. See suggestions below.

