Kisspeptin is a neuropeptide that binds KISS1R (formerly GPR54) receptors on gonadotropin-releasing hormone (GnRH) neurons in the hypothalamus. By stimulating GnRH secretion, it sits at the apex of the reproductive endocrine axis, driving LH and FSH release.
Beyond reproduction, research has identified roles in metabolism, mood, and inflammation — extending interest to hypothalamic amenorrhea, fertility, and metabolic models.
- KISS1R / GnRH axis research
- Reproductive endocrinology and fertility studies
- Hypothalamic amenorrhea models
- Metabolism and inflammatory-pathway investigation
- CAS
- 374675-21-5
- MW
- 1302.4
- Formula
- C₆₃H₈₃N₁₇O₁₄
- Sequence
- H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
Lyophilized vial stable at 2–8 °C; -20 °C for long-term storage. Reconstitute with sterile bacteriostatic water; reconstituted solution stable for up to 30 days at 2–8 °C.
For research and laboratory use only. Not for human or veterinary consumption.
How to run this compound.
Add bacteriostatic water to the sealed vial. Swirl — do not shake. Refrigerate after reconstitution.
Reconstitute with bacteriostatic water. Subcutaneous administration on protocol cadence.
Run on the protocol schedule. The system rewards consistency over intensity.
Pair with complementary REFRAME lines. See suggestions below.